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Vertigo

Vertigo

Vertigo is a sensation of irregular or whirling motion, either of oneself or of external objects. The word is sometimes incorrectly used as a general term to describe dizziness. The most common form of vertigo is benign positional paroxysmal vertigo (BPPV), in which brief attacks are brought on by certain changes in head position. BPPV may be due to a previous head injury, viral infection, and certain drug therapies, although in about half the cases the cause is unknown. BPPV tends to resolve without treatment within weeks to months, but may persist for years in some cases.

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Vitamin B12 Deficiency

Vitamin B12 Deficiency

Vitamin B12 (cobalamin) deficiency is a factor in many disorders. The absorption of dietary vitamin B12 occurs in the small intestine and requires a secretion from the stomach known as intrinsic factor. If intrinsic factor is deficient, absorption of vitamin B12 is severely diminished. Vitamin B12 deficiency impairs the body’s ability to make blood, accelerates blood cell destruction, and damages the nervous system. The result is pernicious anemia (PA). In the classical definition, PA refers only to B12 deficiency anemia caused by a lack of intrinsic factor.

True PA is probably an autoimmune disease. The immune system destroys cells in the stomach that secrete intrinsic factor. Many people with PA have both chronic inflammation of the stomach lining, called atrophic gastritis, and antibodies that fight their intrinsic factor-secreting cells.

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Vitamin B12 Deficiency Anemia

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Vitiligo

Vitiligo

Vitiligo is a type of skin discoloration characterized by progressively widening areas of depigmented (very white) skin. The depigmentation that occurs with this condition is associated with the local destruction of melanocytes, the cells that produce the pigment that darkens the skin, called melanin. Vitiligo affects 1–4% of the world’s population.

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Vulvovaginitis

Vaginitis

Vaginitis, inflammation of the vagina, is responsible for an estimated 10% of all visits by women to their healthcare practitioners. The three general causes of vaginitis are hormonal imbalance, irritation, and infection. Hormone-related vaginitis includes the atrophic vaginitis generally found in postmenopausal or postpartum women and, occasionally, in young girls before puberty. Irritant vaginitis can result from allergies or irritating substances. Infectious vaginitis is most common in reproductive-age women and is generally caused by one of three types of infections: bacterial vaginosis (BV), candidiasis (yeast infection), or trichomoniasis. A healthcare professional should be consulted for the diagnosis and treatment of any vaginal infection.